名稱 | RET p.M918T Reference Standard 標準品 |
型號 | CBP10483 |
報價 | ![]() |
特點 | RET p.M918T Reference Standard |
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聯系人:蔣經理
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區緯地路9號
Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區緯地路9號
Email: zhangxiangwen@cobioer.com
產品展示 / PRODUCTS

- 詳細內容
CBP10483 | |
Format | Genomic DNA |
Description | RET M918T lies within the protein kinase domain of the Ret protein (Uniprot.org). M918T results in ligand-independent autophosphorylation of Ret and increased substrate binding, is transforming (PMID: 17108110), and confers drug resistance in the context of KIF5B-RET in culture (PMID: 29908090). |
Technical Data | |
DNA Change: | c.2753T>C |
AA Change | p.M918T |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 75% |
Transcript | ENST00000355710.7 |
Cosmic ID | COSM965 |
Chr position(GRCh37) | chr10:43617416 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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