名稱 | PIK3CA p.K111E Reference Standard 標(biāo)準(zhǔn)品 |
型號 | CBP10329 |
報價 | ![]() |
特點(diǎn) | PIK3CA p.K111E Reference Standard |
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電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10329PIK3CA p.K111E Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
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CBP10329 | |
Format | Genomic DNA |
Description | PIK3CA K111E lies within the region linking the PI3K-ABD and PI3K-RBD domains of the Pik3ca protein (UniProt.org). K111E confers a gain of function on the Pik3ca protein as indicated by increased lipid kinase activity and phosphorylation of Akt in cell culture (PMID: 22949682, PMID: 17376864) and demonstrates increased transformation ability in two different cell lines, as compared to wild-type Pik3ca (PMID: 29533785). |
Technical Data | |
DNA Change | c.331A>G |
AA Change | p.K111E |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 33.33% |
Transcript | NM_006218.1 |
Cosmic ID | COSM13570 |
Chr position(GRCh37) | chr3:178916944 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |