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基因檢測標準品 > Mutation > CBP10426AI-Edigene® BRAF p.V600R Reference Standard P

AI-Edigene® BRAF p.V600R Reference Standard P
名稱 AI-Edigene® BRAF p.V600R Reference Standard P
型號 CBP10426
報價
特點 AI-Edigene® BRAF p.V600R Reference Standard Plus
  • 詳細內容
 CBP10426
FormatGenomic DNA
DescriptionBRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040).
  
Technical Data 
DNA Changec.1798_1799GT>AG
AA Changep.V600R
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptENST00000288602
Cosmic IDCOSM474
Chr position(GRCh37)chr7:140453136_140453137
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10426.png

Storage4℃
Expiry36 months from the date of manufacture

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