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藥靶細胞株 > GPCR細胞株 > CBP71357CXCR2/CHO

CXCR2/CHO
名稱 CXCR2/CHO
型號 CBP71357
報價
特點 CXCR2/CHO 凍存條件:90% FBS+10% DMSO
  • 詳細內容
CBP71357
I. Background

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system (Gi/o-coupled[6]). This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. In addition, it binds ligands CXCL2, CXCL3, and CXCL5.


II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXCR2 receptor

Transducer:N/A

Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data

Figure 2. IL -8 effect on CXCR2/CHO-K1 clone 7.





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