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藥靶細胞株 > kinase激酶細胞株 > CBP73319Her2 L755S/BaF3

Her2 L755S/BaF3
名稱 Her2 L755S/BaF3
型號 CBP73319
報價
特點 Her2 L755S/BaF3
  • 詳細內容


CBP73319
I. Introduction

Cell Line Name:

Her2 L755S/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative


II.Background

ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238).


III. Representative Data

1.Sanger of Her2 L755S/BaF3

2. Anti-proliferation assay

Figure 2. CTG Proliferation Assay of BaF3 Her2 L755S (C1).










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